Ser171
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Home > Phosphorylation Site Page: > Ser171  -  IRF3 (mouse)

Site Information
DPSQQLPsPNVNNFL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6370303

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 3 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 3 ) , liver ( 1 )

Upstream Regulation
Kinases, in vitro:
ERK1 (mouse) ( 2 )
Treatments:
insulin ( 3 )

References 

1

Robles MS, Humphrey SJ, Mann M (2017) Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. Cell Metab 25, 118-127
27818261   Curated Info

2

Moore TC, Petro TM (2013) IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C. FEBS Lett 587, 3014-20
23892079   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info