Ser251
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Home > Phosphorylation Site Page: > Ser251  -  Snail2 (human)

Site Information
KNCsKTFsRMsLLHK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 63243400

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 ) , breast cancer, triple negative ( 1 ) , prostate cancer ( 1 )
Relevant cell line - cell type - tissue:
BT-549 (breast cell) ( 1 ) , LNCaP (prostate cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PAK1 (human) ( 1 )
Kinases, in vitro:
PAK1 (human) ( 1 )

Downstream Regulation
Effects of modification on Snail2:
intracellular localization ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Thaper D, et al. (2017) Targeting Lyn regulates Snail family shuttling and inhibits metastasis. Oncogene 36, 3964-3975
28288135   Curated Info

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