Lys143
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Home > Acetylation Site Page: > Lys143  -  eIF2-alpha (human)

Site Information
WVFDDkYkRPGyGAy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 63112800

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
H9c2 (myoblast) ( 1 ) , myocardium ( 1 )

Upstream Regulation
Treatments:
selisistat ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, induced ( 1 )

References 

1

Prola A, et al. (2017) SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation. Cell Death Differ 24, 343-356
27911441   Curated Info