Lys143

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Home > Acetylation Site Page: > Lys143 - eIF2-alpha (human)

Site Information
WVFDDkYkRPGyGAy SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 63112800

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	H9c2 (myoblast) ( 1 ) , myocardium ( 1 )

Upstream Regulation
Treatments:	selisistat ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on biological processes:	apoptosis, induced ( 1 )

References
1	Prola A, et al. (2017) SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation. Cell Death Differ 24, 343-356 27911441 Curated Info

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