Lys285
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Home > Ubiquitylation Site Page: > Lys285  -  Ku80 (human)

Site Information
VVDAkTLkKEDIQkE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 62489909

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 ) , lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on Ku80:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
DNA repair, induced ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Ishida N, et al. (2017) Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair. Mol Cell Biol 37
27895153   Curated Info