Ser515
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Home > Phosphorylation Site Page: > Ser515  -  JAK1 (human)

Site Information
SLHGSDRsFPsLGDL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 62372200

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
AMPKA1 (human) ( 1 )

Downstream Regulation
Effects of modification on JAK1:
molecular association, regulation ( 1 )

References 

1

Rutherford C, et al. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Sci Signal 9, ra109
27919027   Curated Info