Tyr99

Site Information
DVtGAQAyASTAKCL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 473647

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 , 4 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	liver cancer ( 1 ) , hepatocellular carcinoma ( 1 ) , lung cancer ( 2 ) , non-small cell lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 ) , non-small cell squamous cell lung carcinoma ( 2 )
Relevant cell line - cell type - tissue:	BEAS-2B (epithelial) ( 3 ) , Flp-In T-Rex-293 (epithelial) ( 1 ) , Huh7 (hepatic) ( 1 ) , Jurkat (T lymphocyte) ( 4 ) , NCI-H1703 (squamous) ( 2 )

References
1	Zhao X, et al. (2017) Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses. J Virol 29263263 Curated Info
2	Rikova K (2012) CST Curation Set: 13328; Year: 2012; Biosample/Treatment: cell line, NCI-H1703/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
3	Rikova K (2009) CST Curation Set: 6680; Year: 2009; Biosample/Treatment: cell line, Dana Farber BEAS/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
4	Possemato A (2007) CST Curation Set: 2928; Year: 2007; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info