Thr407
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr407  -  TRPV1 (mouse)

Site Information
IAYSSSEtPNRHDML   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 473576

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
MDPC-23 (dental pulp cells) ( 2 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 2 )
Treatments:
SB431542 ( 2 ) , seliciclib ( 2 ) , TGF-beta ( 2 )

Downstream Regulation
Effects of modification on TRPV1:
activity, induced ( 2 )

References 

1

Cho A, et al. (2022) Nociceptive signaling through transient receptor potential vanilloid 1 is regulated by Cyclin Dependent Kinase 5-mediated phosphorylation of T407 in vivo. Mol Pain 18, 17448069221111473
35726573   Curated Info

2

Utreras E, et al. (2013) TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells. Mol Pain 9, 24
23668392   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.