Tyr30
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Home > Phosphorylation Site Page: > Tyr30  -  Fos (human)

Site Information
AGDSLSYyHsPADSF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 473044

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
brain cancer ( 2 ) , glioblastoma ( 2 ) , glioblastoma multiforme ( 1 , 2 ) , glioma ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )
Kinases, in vitro:
Src (human) ( 1 )
Putative upstream phosphatases:
PTPN2 (human) ( 1 )
Phosphatases, in vitro:
PTPN2 (human) ( 1 )

Downstream Regulation
Effects of modification on Fos:
intracellular localization ( 2 )
Effects of modification on biological processes:
cell cycle regulation ( 1 ) , cell growth, inhibited ( 1 )

References 

1

Ferrero GO, Velazquez FN, Caputto BL (2012) The kinase c-Src and the phosphatase TC45 coordinately regulate c-Fos tyrosine phosphorylation and c-Fos phospholipid synthesis activation capacity. Oncogene 31, 3381-91
22105363   Curated Info

2

Portal MM, Ferrero GO, Caputto BL (2007) N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation. Oncogene 26, 3551-8
17160021   Curated Info