Lys116
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Home > Acetylation Site Page: > Lys116  -  Snail2 (human)

Site Information
EEERLQSkLSDPHAI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 59171802

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , MCF10A1 (epithelial) ( 1 ) , SUM1315MO2 (epidermal) ( 1 ) , SUM149 (breast cell) ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 ) , sirtinol ( 1 )

Downstream Regulation
Effects of modification on Snail2:
protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
carcinogenesis, inhibited ( 1 ) , transcription, induced ( 1 )

References 

1

Zhou W, et al. (2016) The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer. Cell Rep 17, 1302-1317
27783945   Curated Info

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