Lys216
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Home > Acetylation Site Page: > Lys216  -  VGLL4 (mouse)

Site Information
HFRRSLGkNYKEPEP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 59149206

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Treatments:
development ( 1 )

Downstream Regulation
Effects of modification on VGLL4:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 ) , cell growth, induced ( 1 ) , signaling pathway regulation ( 1 ) , transcription, induced ( 1 )
Inhibit interaction with:
TEAD1 (human) ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
cardiomyopathy ( 1 )

References 

1

Lin Z, et al. (2016) Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth. Dev Cell 39, 466-479
27720608   Curated Info