Ser63
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Home > Phosphorylation Site Page: > Ser63  -  STMN1 (rat)

Site Information
AAEERRKsHEAEVLk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448557

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 1 ) , mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:
'brain, brainstem' ( 3 ) , 'brain, cerebellum' ( 3 ) , 'brain, cerebral cortex' ( 3 ) , adipose tissue ( 3 ) , blood ( 3 ) , COS (fibroblast) ( 1 ) , IEC-6 (epithelial) ( 2 ) , intestine ( 3 ) , kidney ( 3 ) , lung ( 3 ) , PC-12 (chromaffin) ( 1 ) , spleen ( 3 ) , testis ( 3 ) , thymus ( 3 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Kinases, in vitro:
PKACA (rat) ( 1 )
Treatments:
arsenite ( 1 ) , bisindolylmaleimide ( 1 ) , cholera_toxin ( 1 ) , EGF ( 1 ) , glucose_oxidase ( 1 ) , H-89 ( 1 ) , H2O2 ( 1 ) , heat_shock ( 1 ) , JNK_inhibitor_VIII ( 1 ) , NGF ( 1 ) , NKH_477 ( 1 ) , osmotic_stress ( 1 ) , serum ( 2 ) , sorbitol ( 1 ) , staurosporine ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Yip YY, Yeap YY, Bogoyevitch MA, Ng DC (2014) cAMP-dependent Protein Kinase and c-Jun N-terminal Kinase Mediate Stathmin Phosphorylation for the Maintenance of Interphase Microtubules during Osmotic Stress. J Biol Chem 289, 2157-69
24302736   Curated Info

2

Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012   Curated Info

3

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info