Tyr618
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Home > Phosphorylation Site Page: > Tyr618  -  APS (rat)

Site Information
ARAVENQySFY____   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448842

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
INSR (rat) ( 1 )
Treatments:
insulin ( 1 )

Downstream Regulation
Effects of modification on APS:
molecular association, regulation ( 1 )
Induce interaction with:
Cbl-c (human) ( 1 )

References 

1

Liu J, Kimura A, Baumann CA, Saltiel AR (2002) APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes. Mol Cell Biol 22, 3599-609
11997497   Curated Info