Ser633
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Home > Phosphorylation Site Page: > Ser633  -  TIF1A (human)

Site Information
SFDTHFRsPssSVGs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448838

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK1 (human) ( 2 )
Treatments:
PD98059 ( 2 )

Downstream Regulation
Effects of modification on biological processes:
cell growth, induced ( 1 ) , transcription, induced ( 1 )

References 

1

Gomes C, et al. (2011) RNA polymerase 1-driven transcription as a mediator of BDNF-induced neurite outgrowth. J Biol Chem 286, 4357-63
21098478   Curated Info

2

Zhao J, Yuan X, Frödin M, Grummt I (2003) ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol Cell 11, 405-13
12620228   Curated Info