Thr59

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Home > Phosphorylation Site Page: > Thr59 - PKG1 (human)

Site Information
THIGPRTtRAQGIsA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1870119330

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Kinases, in vitro:	PKCA (human) ( 1 )
Treatments:	cGMP_analog ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on PKG1:	enzymatic activity, induced ( 1 )

References
1	Hou Y, et al. (2003) Activation of cGMP-dependent protein kinase by protein kinase C. J Biol Chem 278, 16706-12 12609995 Curated Info

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