Lys440
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Home > Acetylation Site Page: > Lys440  -  FOXM1 (human)

Site Information
LSSAGPGkEEKLLFG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 57807003

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
293T (epithelial) ( 1 ) , U2OS (bone cell) ( 1 )

Downstream Regulation
Effects of modification on FOXM1:
activity, induced ( 1 ) , molecular association, regulation ( 1 ) , phosphorylation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell growth, induced ( 1 ) , transcription, induced ( 1 )

References 

1

Lv C, et al. (2016) Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation. Oncotarget 7, 60366-60382
27542221   Curated Info