Ser218
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Home > Phosphorylation Site Page: > Ser218  -  ACC2 (rat)

Site Information
PTMRPSMsGLHLVKR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448808

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 2 , 3 , 4 , 5 ) , western blotting ( 1 , 2 , 3 , 4 , 5 )
Relevant cell line - cell type - tissue:
'muscle, skeletal' ( 1 , 2 , 3 , 5 ) , CHO (fibroblast) ( 5 ) , L6 (myoblast) ( 4 )

Upstream Regulation
Treatments:
acadesine ( 2 , 5 ) , caffeine ( 3 ) , compound_C ( 5 ) , exercise ( 2 ) , fasting ( 1 ) , insulin ( 1 , 5 ) , linoleic_acid ( 4 ) , muscle contraction ( 1 ) , palmitate ( 4 ) , refeeding ( 1 )

References 

1

Lai YC, Zarrinpashneh E, Jensen J (2010) Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents. J Appl Physiol 108, 1106-15
20185632   Curated Info

2

McConell GK, et al. (2008) Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment. J Appl Physiol 105, 1422-7
18703760   Curated Info

3

Jensen TE, et al. (2007) Caffeine-induced Ca(2+) release increases AMPK-dependent glucose uptake in rodent soleus muscle. Am J Physiol Endocrinol Metab 293, E286-92
17405829   Curated Info

4

Watt MJ, et al. (2006) Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes. J Physiol 574, 139-47
16644805   Curated Info

5

Hutchinson DS, Bengtsson T (2006) AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake. Diabetes 55, 682-90
16505231   Curated Info