Ser679
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser679  -  IKKB (mouse)

Site Information
sPDsMNVsRLsHPGQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 5735027

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 2 ) , macrophage-peritoneum ( 1 )

Upstream Regulation
Putative in vivo kinases:
IKKB (mouse) ( 2 )
Treatments:
wedelolactone ( 2 )

Downstream Regulation
Effects of modification on IKKB:
molecular association, regulation ( 2 ) , phosphorylation ( 2 )
Induce interaction with:
PPP2R3C (human) ( 2 )

References 

1

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

2

Chiang CW, Liu WK, Chiang CW, Chou CK (2010) Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5. Biochem J 433, 187-96
20925653   Curated Info