Ser361
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Home > Phosphorylation Site Page: > Ser361  -  FOXM1 iso2 (human)

Site Information
PLLPRVSsYLVPIQF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 471396

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
U2OS (bone cell) [GR (human)] ( 1 )

Upstream Regulation
Putative in vivo kinases:
Chk2 (human) ( 1 )
Kinases, in vitro:
Chk2 (human) ( 1 )
Treatments:
etoposide ( 1 ) , ionizing_radiation ( 1 )

Downstream Regulation
Effects of modification on FOXM1 iso2:
protein stabilization ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Tan Y, Raychaudhuri P, Costa RH (2007) Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes. Mol Cell Biol 27, 1007-16
17101782   Curated Info

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