Thr748
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Home > Phosphorylation Site Page: > Thr748  -  STAT1 (mouse)

Site Information
EFDsMMstV______   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 56654462

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
macrophage-bone marrow ( 1 ) , macrophage-peritoneum ( 1 ) , RAW 264.7 (macrophage) ( 1 )

Upstream Regulation
Putative in vivo kinases:
IKKB (human) ( 1 )
Kinases, in vitro:
IKKB (mouse) ( 1 )
Treatments:
BMS-345541 ( 1 ) , LPS ( 1 ) , tofacitinib ( 1 )

Downstream Regulation
Effects of modification on biological processes:
endocytosis, induced ( 1 ) , transcription, altered ( 1 )

References 

1

Metwally H, et al. (2024) Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses. Proc Natl Acad Sci U S A 121, e2402226121
38621137   Curated Info