Thr450
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr450  -  Akt1 (rat)

Site Information
TAQMITItPPDQDDS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447857

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
L6 (myoblast) ( 1 ) , myocyte-heart ( 2 )

Upstream Regulation
Treatments:
insulin ( 1 ) , PIK90 ( 1 ) , PP242 ( 1 ) , rapamycin ( 1 )

References 

1

Feldman ME, et al. (2009) Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol 7, e38
19209957   Curated Info

2

Shao Z, et al. (2006) c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. Circ Res 98, 111-8
16306447   Curated Info