Ser692
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Home > Phosphorylation Site Page: > Ser692  -  HIF1A (human)

Site Information
PRsPNVLsVALsQRT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 56589702

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 2 ) , mass spectrometry ( 1 , 2 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 , 2 )

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 1 , 2 )

Downstream Regulation
Effects of modification on HIF1A:
protein stabilization ( 1 , 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

So L, et al. (2016) The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes. Sci Signal 9, ra57
27245614   Curated Info

2

Bullen JW, et al. (2016) Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1. Sci Signal 9, ra56
27245613   Curated Info