Lys241
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Home > Acetylation Site Page: > Lys241  -  TBK1 (mouse)

Site Information
MYkIITGkPSGAISG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 56403910

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , macrophage-peritoneum ( 1 )

Downstream Regulation
Effects of modification on TBK1:
enzymatic activity, inhibited ( 1 )

References 

1

Li X, et al. (2016) Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. Nat Immunol 17, 806-15
27240213   Curated Info