Ser218
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Home > Phosphorylation Site Page: > Ser218  -  MEK1 (rabbit)

Site Information
VSGQLIDsMANsFVG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448514

Upstream Regulation
Kinases, in vitro:
KSR2 (human) ( 1 ) , MOS (human) ( 2 )

Downstream Regulation
Effects of modification on MEK1:
enzymatic activity, induced ( 2 )

References 

1

Brennan DF, et al. (2011) A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK. Nature 472, 366-9
21441910   Curated Info

2

Resing KA, et al. (1995) Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS. Biochemistry 34, 2610-20
7873542   Curated Info