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Powered by Cell Signaling Technology |
| Site Information |
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| NYLRRRLsDsNFMAN SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 448378 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Regulatory protein: | |
| Putative in vivo kinases: | |
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| Downstream Regulation | |
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| Effects of modification on SYN1: | |
| Effects of modification on biological processes: | |
| Inhibit interaction with: | |
| References | |
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Fu T, et al. (2019) Modulation of cPKCγ on Synapsin-Ia/b-Specific Phosphorylation Sites in the Developing Visual Cortex of Mice. Invest Ophthalmol Vis Sci 60, 2676-2684
31242289 Curated Info |
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Zhang N, et al. (2018) cPKCγ alleviates ischemic injury through modulating synapsin Ia/b phosphorylation in neurons of mice. Brain Res Bull 142, 156-162
30016727 Curated Info |
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Park D, et al. (2017) Activation of CaMKIV by soluble amyloid-β1-42 impedes trafficking of axonal vesicles and impairs activity-dependent synaptogenesis. Sci Signal 10
28698220 Curated Info |
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Choi Y, et al. (2017) Clozapine Improves Memory Impairment and Reduces Aβ Level in the Tg-APPswe/PS1dE9 Mouse Model of Alzheimer's Disease. Mol Neurobiol 54, 450-460
26742522 Curated Info |
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Plattner F, et al. (2015) The role of ventral striatal cAMP signaling in stress-induced behaviors. Nat Neurosci 18, 1094-100
26192746 Curated Info |
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Qin Z, et al. (2013) Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent. PLoS One 8, e80758
24224061 Curated Info |
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Davis MM, et al. (2012) Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits. Eur J Neurosci 35, 300-8
22250817 Curated Info |
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Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079 Curated Info |
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Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495 Curated Info |
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Tallent MK, et al. (2009) In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. J Biol Chem 284, 174-81
19004831 Curated Info |
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Nishi A, et al. (2008) Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci 28, 10460-71
18923023 Curated Info |
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John JP, Chen WQ, Pollak A, Lubec G (2007) Mass spectrometric studies on mouse hippocampal synapsins Ia, IIa, and IIb and identification of a novel phosphorylation site at serine-546. J Proteome Res 6, 2695-710
17579389 Curated Info |
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Guo A (2007) CST Curation Set: 2718; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E)
Curated Info |
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Sahin B, et al. (2007) Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling. Brain Res 1129, 1-14
17157277 Curated Info |
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Frederikse PH, et al. (2004) Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation. Mol Vis 10, 794-804
15529118 Curated Info |
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