Ser2
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Home > O-GlcNAc Site Page: > Ser2  -  p27Kip1 (human)

Site Information
______MsNVRVSNG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 55595400

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
PUGNAc ( 1 )

Downstream Regulation
Effects of modification on p27Kip1:
intracellular localization ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 ) , cell growth, induced ( 1 )
Induce interaction with:
Exportin-1 (human) ( 1 )

References 

1

Qiu H, et al. (2017) Modification of p27 with O-linked N-acetylglucosamine regulates cell proliferation in hepatocellular carcinoma. Mol Carcinog 56, 258-271
27175940   Curated Info