Thr370

Site Information
LSGNADDtLSRKLDD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 55571503

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , MDA-MB-231 (breast cell) ( 1 ) , SKBR7 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on PRICKLE1:	molecular association, regulation ( 1 )
Effects of modification on biological processes:	cell growth, induced ( 1 ) , cell motility, induced ( 1 )
Induce interaction with:	RICTOR (human) ( 1 )

References
1	Daulat AM, et al. (2016) PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2. Dev Cell 37, 311-25 27184734 Curated Info