Tyr64
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Home > Phosphorylation Site Page: > Tyr64  -  PKCD (rat)

Site Information
STFDAHIyEGRVIQI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447581

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
Abi-1 (human) ( 1 )
Putative in vivo kinases:
Src (human) ( 1 )
Treatments:
dasatinib ( 1 ) , etoposide ( 1 ) , H2O2 ( 1 ) , imatinib ( 1 ) , mutation ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on PKCD:
intracellular localization ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )

References 

1

Wie SM, et al. (2014) Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damage. J Biol Chem 289, 10900-8
24569990   Curated Info

2

Adwan TS, et al. (2011) Regulated binding of importin-α to protein kinase Cδ in response to apoptotic signals facilitates nuclear import. J Biol Chem 286, 35716-24
21865164   Curated Info