Arg174
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Home > Di-methylation Site Page: > Arg174  -  NFkB-p65 (human)

Site Information
DPSGRPLrLPPVLsH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 54221300

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HUVEC (endothelial) ( 1 )

Upstream Regulation
Treatments:
IFN-gamma ( 1 ) , TNF ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
DNA ( 1 )

References 

1

Harris DP, et al. (2016) PRMT5-Mediated Methylation of NF-κB p65 at Arg174 Is Required for Endothelial CXCL11 Gene Induction in Response to TNF-α and IFN-γ Costimulation. PLoS One 11, e0148905
26901772   Curated Info