Lys367
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Home > Sumoylation Site Page: > Lys367  -  TTK (human)

Site Information
tEssLLAkLEEtkEy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 52485002

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
nocodazole ( 1 ) , taxol ( 1 )

Downstream Regulation
Effects of modification on TTK:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )
Inhibit interaction with:
BUB1B (human) ( 1 )

References 

1

Restuccia A, et al. (2016) Mps1 is SUMO-modified during the cell cycle. Oncotarget 7, 3158-70
26675261   Curated Info

2

Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36
25218447   Curated Info