Tyr396
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Home > Phosphorylation Site Page: > Tyr396  -  SNIP iso5 (human)

Site Information
LVKGEGLyADPYGLL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 456704

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , NCI-H3255 (pulmonary) ( 2 , 3 )

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 )
Kinases, in vitro:
Abl (human) ( 1 ) , ALK (human) ( 1 )
Treatments:
vanadate ( 1 )

Downstream Regulation
Effects of modification on SNIP iso5:
molecular association, regulation ( 1 )
Induce interaction with:
CSK (human) ( 1 )

References 

1

Repetto D, et al. (2013) Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase. PLoS One 8, e54931
23383002   Curated Info

2

Moritz A (2008) CST Curation Set: 5774; Year: 2008; Biosample/Treatment: cell line, NCI-H3255/Iressa; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Moritz A (2008) CST Curation Set: 5775; Year: 2008; Biosample/Treatment: cell line, NCI-H3255/Iressa; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info