Ser729
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Home > Phosphorylation Site Page: > Ser729  -  IRE1 (mouse)

Site Information
RHsFSRRsGVPGTEG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 53407300

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , B cell lymphoma ( 1 ) , multiple myeloma ( 1 )
Relevant cell line - cell type - tissue:
A20 (B lymphocyte) ( 1 ) , B lymphocyte-spleen ( 1 ) , NCI-H929 (B lymphocyte) ( 1 )

Upstream Regulation
Regulatory protein:
XBP1 (mouse) ( 1 )
Treatments:
DTT ( 1 ) , PTX ( 1 ) , Shiga_toxin ( 1 ) , SubAB ( 1 )

Downstream Regulation
Effects of modification on biological processes:
RNA splicing, induced ( 1 )

References 

1

Tang CH, et al. (2018) Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. J Cell Biol
29511123   Curated Info