Thr331
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Home > Phosphorylation Site Page: > Thr331  -  Fos (rat)

Site Information
CtPVVTCtPSCTTYT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448484

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK1 (rat) ( 2 ) , ERK2 (rat) ( 2 )
Kinases, in vitro:
ERK2 (human) ( 2 )
Treatments:
EGF ( 2 ) , NGF ( 1 )

Downstream Regulation
Effects of modification on Fos:
activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )
Induce interaction with:
DNA ( 1 )

References 

1

Pellegrino MJ, Stork PJ (2006) Sustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells. J Neurochem 99, 1480-93
17223854   Curated Info

2

Murphy LO, et al. (2002) Molecular interpretation of ERK signal duration by immediate early gene products. Nat Cell Biol 4, 556-64
12134156   Curated Info