Tyr891
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Home > Phosphorylation Site Page: > Tyr891  -  IRS1 (mouse)

Site Information
EPKsPGEyVNIEFGS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447556

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 3 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 ) , preadipocyte ( 3 )

Upstream Regulation
Treatments:
insulin ( 1 , 3 )

References 

1

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

2

Kumar A, et al. (2010) Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism. Diabetes 59, 1397-406
20332342   Curated Info

3

Kr├╝ger M, et al. (2008) Dissection of the insulin signaling pathway via quantitative phosphoproteomics. Proc Natl Acad Sci U S A 105, 2451-6
18268350   Curated Info