Ser82
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Home > Phosphorylation Site Page: > Ser82  -  DYNLT1 (human)

Site Information
AGLHtAssCFWDSST   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 470041

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 , 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
hypoxia ( 1 )

Downstream Regulation
Effects of modification on DYNLT1:
molecular association, regulation ( 3 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )
Induce interaction with:
Rhodopsin (human) ( 3 )
Inhibit interaction with:
DNCLI1 (human) ( 3 )

References 

1

Xu X, et al. (2013) Phosphorylation of DYNLT1 at serine 82 regulates microtubule stability and mitochondrial permeabilization in hypoxia. Mol Cells 36, 322-32
24170091   Curated Info

2

Possemato A (2008) CST Curation Set: 3661; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS:pSXXXpS
Curated Info

3

Yeh TY, et al. (2006) Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin. Traffic 7, 1495-502
16956385   Curated Info