Lys120

Site Information
TLRFNLPkEREAIPG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 52498000

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	bone cancer ( 1 ) , lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , NCI-H1299 (pulmonary) ( 1 ) , U2OS (bone cell) ( 1 )

Downstream Regulation
Effects of modification on Tip60:	intracellular localization ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:	apoptosis, altered ( 1 )

References
1	Yi J, et al. (2014) Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3. J Biol Chem 289, 33878-86 25301942 Curated Info