Thr532
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Home > Phosphorylation Site Page: > Thr532  -  CLCN3 iso2 (rat)

Site Information
LGGVTRMtVSLVVIV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 51381106

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
hypertension ( 1 )
Relevant cell line - cell type - tissue:
VSMC ( 1 )

Upstream Regulation
Putative in vivo kinases:
ROCK2 (rat) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell motility, induced ( 1 )

References 

1

Ma MM, et al. (2016) Threonine532 phosphorylation in ClC-3 channels is required for angiotensin II-induced Cl(-) current and migration in cultured vascular smooth muscle cells. Br J Pharmacol 173, 529-44
26562480   Curated Info