Ser78
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Home > Phosphorylation Site Page: > Ser78  -  H2B1C (human)

Site Information
AMBIGUOUS SITES: H2B (human): , H2B1D (human): , H2B1H (human): , H2B1K (human): , H2B1M (human): , H2B1N (human): , H2B2E (human): , H2B2F (human): , H2BFH (human): , HIST1H2BJ (human): , HIST2H2BC (human): , HIST2H2BD (human):
ErIAGEAsrLAHyNk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50780190

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 3 ) , mass spectrometry (in vitro) ( 4 )
Disease tissue studied:
luminal B breast cancer ( 1 ) , breast cancer, triple negative ( 1 ) , lung cancer ( 3 ) , non-small cell lung cancer ( 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
AurB (human) ( 4 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

3

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

4

Hengeveld RC, et al. (2012) Development of a chemical genetic approach for human aurora B kinase identifies novel substrates of the chromosomal passenger complex. Mol Cell Proteomics 11, 47-59
22267324   Curated Info