Ser343
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Home > Phosphorylation Site Page: > Ser343  -  ERK1 iso3 (human)

Site Information
PTDEVGQsPAAVGLG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50703500

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK1 (human) ( 1 )
Kinases, in vitro:
CDK1 (human) ( 1 )

Downstream Regulation
Effects of modification on ERK1 iso3:
enzymatic activity, induced ( 1 ) , intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 )
Induce interaction with:
14-3-3 gamma (human) ( 1 ) , PIK4CB (human) ( 1 )

References 

1

Wortzel I, et al. (2015) Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ-14-3-3γ shuttling complex. J Cell Sci 128, 4083-95
26459638   Curated Info

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