Ser17
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser17  -  IKKG (human)

Site Information
LCEMVQPsGGPAADQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50564412

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , 3T3 (fibroblast) ( 1 ) , MCF-7 (breast cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )
Kinases, in vitro:
GSK3B (human) ( 1 )

Downstream Regulation
Effects of modification on IKKG:
protein stabilization ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Medunjanin S, et al. (2016) GSK-3β controls NF-kappaB activity via IKKγ/NEMO. Sci Rep 6, 38553
27929056   Curated Info