Ser33
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser33  -  Ku70 (human)

Site Information
AsGDykYsGRDsLIF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50247606

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 )
Disease tissue studied:
leukemia ( 1 ) , chronic lymphocytic leukemia ( 1 ) , lymphoma ( 1 ) , Burkitt's lymphoma ( 1 )
Relevant cell line - cell type - tissue:
B lymphocyte-blood ( 1 ) , RAMOS (B lymphocyte) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 ) , DNAPK (human) ( 1 )

Downstream Regulation
Effects of modification on Ku70:
intracellular localization ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 ) , cell cycle regulation ( 1 ) , DNA repair, induced ( 1 )

References 

1

Bouley J, et al. (2015) A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines. Oncotarget 6, 27980-8000
26337656   Curated Info