Tyr185
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Site Information
HtGFLtEyVAtRWYR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447594
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 442 , 463 , 551 , 564 , 566 , 567 , 569 ) , flow cytometry ( 165 , 323 ) , immunoprecipitation ( 5 , 8 , 13 , 38 , 43 , 131 , 138 , 196 , 208 , 219 , 556 ) , mass spectrometry ( 4 , 6 , 7 , 11 , 18 , 29 , 35 , 44 , 45 , 46 , 47 , 50 , 51 , 56 , 59 , 60 , 61 , 63 , 64 , 65 , 67 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 95 , 96 , 99 , 128 , 129 , 130 , 134 , 141 , 142 , 143 , 144 , 145 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 181 , 182 , 183 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 194 , 199 , 200 , 201 , 202 , 203 , 204 , 213 , 214 , 215 , 216 , 217 , 220 , 226 , 227 , 228 , 229 , 230 , 231 , 232 , 235 , 236 , 238 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 248 , 249 , 250 , 251 , 252 , 253 , 254 , 255 , 256 , 257 , 258 , 259 , 260 , 261 , 262 , 264 , 265 , 266 , 267 , 268 , 269 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 279 , 280 , 281 , 283 , 284 , 285 , 286 , 287 , 288 , 291 , 292 , 293 , 294 , 295 , 296 , 299 , 302 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 318 , 319 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 340 , 341 , 343 , 344 , 347 , 349 , 350 , 351 , 352 , 353 , 354 , 360 , 366 , 367 , 370 , 371 , 377 , 379 , 380 , 393 , 398 , 399 , 400 , 401 , 402 , 404 , 405 , 406 , 407 , 408 , 411 , 412 , 413 , 414 , 415 , 423 , 424 , 425 , 427 , 428 , 429 , 433 , 434 , 435 , 436 , 438 , 439 , 447 , 448 , 449 , 451 , 452 , 453 , 454 , 455 , 456 , 457 , 458 , 461 , 462 , 467 , 468 , 470 , 471 , 472 , 476 , 477 , 480 , 481 , 482 , 485 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 497 , 499 , 504 , 505 , 507 , 566 , 569 ) , mass spectrometry (in vitro) ( 133 ) , microscopy-colocalization with upstream kinase ( 529 ) , mutation of modification site ( 5 , 8 , 13 , 219 , 222 , 289 , 298 , 385 , 386 , 389 , 442 , 445 , 446 , 463 , 562 , 564 ) , phospho-antibody ( 1 , 2 , 3 , 5 , 8 , 9 , 10 , 12 , 13 , 14 , 15 , 16 , 17 , 20 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 34 , 37 , 38 , 39 , 40 , 42 , 43 , 48 , 53 , 54 , 55 , 57 , 66 , 67 , 68 , 70 , 84 , 85 , 90 , 93 , 94 , 97 , 98 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 131 , 132 , 135 , 136 , 137 , 138 , 139 , 140 , 146 , 147 , 148 , 149 , 150 , 151 , 165 , 166 , 175 , 179 , 180 , 184 , 193 , 195 , 196 , 197 , 198 , 206 , 207 , 208 , 209 , 210 , 211 , 212 , 218 , 219 , 221 , 222 , 223 , 224 , 233 , 234 , 237 , 239 , 270 , 282 , 289 , 290 , 297 , 298 , 300 , 303 , 304 , 315 , 317 , 320 , 321 , 322 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 339 , 342 , 345 , 346 , 348 , 355 , 356 , 357 , 358 , 359 , 361 , 362 , 363 , 364 , 365 , 368 , 369 , 372 , 373 , 374 , 375 , 376 , 378 , 381 , 382 , 383 , 384 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 394 , 395 , 396 , 397 , 403 , 418 , 419 , 420 , 422 , 426 , 430 , 431 , 432 , 437 , 440 , 441 , 442 , 443 , 444 , 445 , 446 , 450 , 459 , 460 , 464 , 465 , 466 , 469 , 473 , 474 , 475 , 478 , 479 , 483 , 484 , 493 , 494 , 495 , 497 , 498 , 500 , 501 , 502 , 503 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 520 , 521 , 522 , 523 , 524 , 525 , 526 , 527 , 528 , 529 , 530 , 531 , 532 , 533 , 534 , 535 , 536 , 537 , 538 , 540 , 541 , 542 , 543 , 544 , 545 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 563 , 564 ) , phosphopeptide mapping ( 551 , 567 , 569 ) , western blotting ( 1 , 2 , 3 , 5 , 8 , 9 , 10 , 12 , 13 , 14 , 15 , 16 , 17 , 20 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 34 , 37 , 38 , 39 , 40 , 42 , 43 , 48 , 53 , 54 , 55 , 57 , 66 , 67 , 68 , 70 , 84 , 85 , 90 , 93 , 94 , 97 , 98 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 131 , 132 , 135 , 136 , 137 , 138 , 139 , 140 , 146 , 147 , 148 , 149 , 150 , 151 , 165 , 166 , 179 , 180 , 184 , 193 , 195 , 196 , 197 , 198 , 206 , 207 , 208 , 209 , 210 , 211 , 212 , 218 , 219 , 221 , 222 , 223 , 224 , 233 , 234 , 237 , 239 , 270 , 282 , 289 , 290 , 297 , 298 , 300 , 303 , 315 , 317 , 320 , 321 , 322 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 339 , 342 , 345 , 346 , 348 , 355 , 356 , 358 , 361 , 362 , 363 , 364 , 365 , 368 , 369 , 372 , 373 , 374 , 375 , 376 , 378 , 381 , 382 , 383 , 384 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 394 , 395 , 396 , 397 , 418 , 422 , 430 , 431 , 437 , 445 , 460 , 464 , 465 , 466 , 469 , 473 , 474 , 478 , 479 , 483 , 484 , 494 , 495 , 498 , 500 , 501 , 503 , 508 , 510 , 511 , 512 , 513 , 514 , 515 , 517 , 518 , 520 , 521 , 524 , 525 , 526 , 528 , 531 , 534 , 535 , 540 , 541 , 542 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 556 , 557 , 558 , 561 , 562 , 563 )
Disease tissue studied:
adrenal cancer ( 517 ) , pheochromocytoma ( 517 ) , breast cancer ( 3 , 131 , 373 , 385 , 550 ) , cervical cancer ( 521 ) , cervical adenocarcinoma ( 521 ) , colorectal cancer ( 484 ) , colorectal carcinoma ( 484 ) , leukemia ( 59 , 189 , 190 , 191 , 192 , 290 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 485 , 486 , 487 , 488 , 489 , 542 ) , acute myelogenous leukemia ( 59 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 290 , 542 ) , chronic myelogenous leukemia ( 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 485 , 486 , 487 , 488 , 489 ) , liver cancer ( 389 ) , lung cancer ( 111 , 277 , 279 , 280 , 281 , 283 , 284 , 285 , 291 , 292 , 293 , 294 , 295 , 296 , 348 , 376 , 465 ) , mesothelioma ( 465 ) , non-small cell lung cancer ( 111 , 128 , 277 , 279 , 280 , 281 , 291 , 292 , 293 , 294 , 295 , 296 ) , lymphoma ( 470 , 527 ) , B cell lymphoma ( 527 ) , neuroblastoma ( 99 , 105 , 479 , 503 , 520 ) , pancreatic cancer ( 131 , 148 , 300 ) , pancreatic carcinoma ( 131 , 148 , 300 ) , prostate cancer ( 67 ) , melanoma skin cancer ( 66 , 213 , 219 ) , testicular cancer ( 142 , 144 , 494 ) , diabetes mellitus ( 221 , 389 ) , type 2 diabetes ( 221 , 389 ) , Huntington's disease ( 38 ) , Turner-like syndrome ( 216 , 217 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 6 , 18 , 32 , 46 ) , 'B lymphocyte, precursor' ( 289 ) , 'brain, cerebellum' ( 51 , 437 , 548 ) , 'brain, cerebral cortex' ( 5 , 374 , 430 , 475 , 543 ) , 'brain, cerebrum' ( 437 , 548 ) , 'brain, embryonic' ( 287 , 349 , 351 ) , 'brain, embryonic' [BAG1 (mouse)] ( 421 ) , 'brain, hippocampus' ( 40 , 146 , 209 , 356 , 390 , 502 ) , 'brain, hippocampus' [DLG3 (mouse), homozygous knockout] ( 355 ) , 'brain, hypothalamus, suprachiasmatic nucleus' ( 444 ) , 'brain, striatum' ( 38 , 224 , 361 , 432 , 464 , 478 , 495 , 537 ) , 'epithelial, lung' [homozygous knockout] ( 119 ) , 'liver, fetal' ( 388 ) , 'muscle, skeletal' ( 195 , 282 ) , 'neuron, cortical'-brain ( 39 , 55 , 138 , 522 ) , 'neuron, cortical'-brain [NYAP2 (mouse), homozygous knockout] ( 70 ) , 'neuron, dorsal horn'-spinal cord ( 304 ) , 'neuron, hippocampal'-brain [neurogranin (mouse)] ( 534 ) , 'neuron, superior cervical ganglion' ( 234 ) , 'renal, podocyte' ( 126 ) , 'stem, embryonic' ( 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 282 ) , 'stem, mesenchymal' ( 318 , 319 ) , 21T (breast cell) ( 131 ) , 293 (epithelial) [DOR-1 (mouse)] ( 554 ) , 293 (epithelial) ( 33 , 211 , 445 , 446 , 551 ) , 32D (myeloid) ( 109 , 514 , 557 ) , 32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ( 175 ) , 3T3 (fibroblast) [CDC42 (human), transfection] ( 44 ) , 3T3 (fibroblast) [INSR (human)] ( 551 ) , 3T3 (fibroblast) [INSR (mouse), transfection] ( 208 ) , 3T3 (fibroblast) [KRas (human), transfection] ( 44 ) , 3T3 (fibroblast) [Pyk2 (human), transfection, stable Pyk2 (v5-His tagged) transfection, in RU-486 (mifepristone)-inducible expression system] ( 134 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 403 , 419 , 443 , 445 , 463 , 465 , 466 , 512 , 516 , 533 , 559 , 562 , 563 ) , 3T3 (fibroblast) [Src (human)] ( 376 ) , 3T3 (fibroblast) ( 2 , 44 , 112 , 196 , 208 , 317 , 381 , 386 , 431 , 454 , 455 , 456 , 457 , 458 , 483 , 499 , 504 , 505 , 507 , 521 , 525 , 541 , 558 , 561 ) , 3T3-L1 (fibroblast) ( 54 , 93 , 147 , 327 , 329 , 339 , 393 , 508 ) , 4T1 (breast cell) ( 385 , 550 ) , 831/13 ( 490 , 491 , 492 ) , AB.1 (T lymphocyte) ( 123 ) , adipocyte-adipose tissue ( 547 ) , adipose tissue ( 282 ) , adipose tissue [DUSP6 (mouse), homozygous knockout] ( 34 ) , alphaT3-1 (pituitary cell) ( 42 ) , aorta ( 358 ) , artery ( 297 ) , B lymphocyte ( 76 , 77 , 289 ) , B lymphocyte-spleen ( 137 , 364 ) , B lymphocyte-spleen [PTEN (mouse), transgenic] ( 166 ) , B16 (melanocyte) ( 66 ) , B16F1 (melanocyte) ( 219 ) , B16F10 ( 10 ) , BAC1.2F5 (macrophage) ( 536 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 376 ) , BaF3 ('B lymphocyte, precursor') [FLT3 (human)] ( 391 ) , BaF3 ('B lymphocyte, precursor') ( 48 , 135 , 149 , 188 , 208 , 218 , 290 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 328 , 369 , 404 , 405 , 406 , 407 , 408 , 411 , 412 , 413 , 414 , 415 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 433 , 434 , 435 , 436 , 438 , 439 , 447 , 448 , 449 , 451 , 467 , 468 , 471 , 472 , 476 , 477 , 485 , 486 , 487 , 488 , 489 , 514 , 526 ) , BALB/MK (keratinocyte) ( 556 ) , beta-pancreas ( 148 ) , beta-pancreas [INSR (mouse), transgenic] ( 127 ) , bladder ( 303 ) , blood ( 59 ) , BMMC (mast) ( 37 , 116 , 552 ) , bone marrow ( 9 , 369 ) , brain ( 60 , 63 , 64 , 130 , 185 , 186 , 187 , 286 , 302 , 347 , 350 , 352 , 529 ) , brain [DARPP-32 (mouse), homozygous knockout] ( 469 ) , brain [NYAP2 (mouse), homozygous knockout] ( 70 ) , C2C12 (myoblast) ( 12 , 235 , 236 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 460 , 510 ) , C2C12-D (muscle cell) ( 353 , 354 ) , C3H10T1/2 (fibroblast) ( 264 , 265 , 266 , 267 , 368 ) , CCE ( 474 ) , CHO (fibroblast) ( 8 ) , CMT-93 (intestinal) ( 484 ) , colon ( 122 ) , COS (fibroblast) ( 17 , 48 , 208 , 383 , 483 , 523 , 524 ) , Dede (fibroblast) ( 564 ) , dendritic cell ( 1 , 317 ) , dendritic cell [MAPKAPK2 (mouse), homozygous knockout] ( 317 ) , dendritic cell [MSK1 (mouse), homozygous knockout] ( 317 ) , E14 ('neuron, hippocampal') ( 57 ) , E14tg2a ('stem, embryonic') ( 14 , 474 ) , EL-4 (T lymphocyte) ( 567 , 569 ) , embryo ( 64 , 388 ) , endothelial-pulmonary artery ( 132 ) , endothelial-vein ( 132 ) , epithelial-'kidney, tubule' ( 322 ) , epithelial-lens ( 342 ) , erythroblast ( 290 ) , ES (stem) ( 33 , 395 , 397 ) , F9 (testicular) ( 142 , 494 ) , Fao (hepatic) ( 389 ) , fibroblast-embryo [BAG1 (mouse)] ( 421 ) , fibroblast-lung ( 194 ) , GL261 (glial) ( 150 ) , GT1-7 (neuron) ( 320 , 392 ) , HaCaT (keratinocyte) ( 321 ) , heart ( 47 , 211 , 214 , 215 , 216 , 217 , 249 , 250 , 251 , 282 , 324 , 341 , 343 , 372 ) , HEK293T (epithelial) ( 8 , 55 , 131 , 562 ) , HEL (erythroid) ( 290 ) , HeLa (cervical) ( 108 , 463 ) , HeLa S3 (cervical) ( 521 ) , Hepa 1-6 (epithelial) ( 220 ) , hepatocyte ( 397 ) , HepG2 (hepatic) ( 389 ) , HT-22 (neuron) ( 522 ) , HT-4 (neuron) ( 522 ) , HUVEC (endothelial) ( 107 , 139 ) , IBE (endothelial) ( 528 ) , J2E (erythroblast) ( 542 ) , J774 (macrophage) ( 513 , 531 ) , JB (epithelial) ( 545 ) , JB6 RT101 (epidermal) ( 396 ) , Jurkat (T lymphocyte) ( 222 ) , keratinocyte ( 84 ) , liver ( 4 , 45 , 56 , 64 , 207 , 282 , 288 , 336 , 337 , 338 , 340 , 344 , 360 , 389 , 480 , 481 , 482 , 538 ) , liver [Akt2 (mouse), homozygous knockout] ( 332 , 333 , 334 , 335 ) , LLC-PK1 (renal) ( 501 ) , lung ( 128 , 238 , 277 , 279 , 280 , 281 , 348 , 366 , 367 ) , lung [EGFR (mouse), transgenic, mutant] ( 284 ) , lung [EGFR (mouse), transgenic] ( 283 ) , lung [HRas (mouse), transgenic] ( 285 ) , lung [p27Kip1 (mouse), genetic knockin] ( 94 ) , macrophage ( 383 ) , macrophage-blood ( 446 ) , macrophage-bone marrow ( 20 , 53 , 330 , 357 , 363 ) , macrophage-bone marrow [Cot (mouse)] ( 315 ) , macrophage-bone marrow [NFkB-p105 (human)] ( 315 ) , macrophage-peritoneum ( 13 , 104 , 553 ) , mast-bone marrow ( 16 , 124 , 210 , 305 , 364 , 384 , 518 ) , mast-bone marrow [PTPRA (mouse), homozygous knockout] ( 223 ) , mast-bone marrow [SHP-2 (mouse), homozygous knockout] ( 179 ) , MC/9 (mast) ( 514 ) , MC3T3-E1 (preosteoblast) ( 11 ) , MCP-5 (mast) ( 305 ) , MCT cells (epithelial) ( 221 ) , MDA-MB-231 (breast cell) ( 3 ) , MEDF [HRas (mouse), HRas V12, HDAC6 -/+] ( 199 , 200 ) , MEF (fibroblast) ( 13 , 50 , 68 , 96 , 108 , 118 , 184 , 201 , 204 , 232 , 248 , 270 , 298 , 321 , 325 , 331 , 345 , 370 , 371 , 372 , 378 , 379 , 380 , 383 , 385 , 386 , 387 , 473 , 511 , 545 , 546 , 549 ) , MEF (fibroblast) [HRas (mouse), HRas V12] ( 202 , 203 ) , MEF (fibroblast) [IGF1R (mouse)] ( 359 , 420 , 440 , 459 , 493 ) , MEF (fibroblast) [LKB1 (mouse)] ( 500 ) , MEF (fibroblast) [MSK1 (mouse), homozygous knockout, msk2] ( 540 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 95 ) , MEF (fibroblast) [PDGFRA (mouse), genetic knockin] ( 206 ) , MEF (fibroblast) [PKR (mouse), homozygous knockout] ( 114 ) , MEF (fibroblast) [PTP1B (mouse), homozygous knockout] ( 232 ) , MEF (fibroblast) [RAF1 (mouse), homozygous knockout] ( 233 ) , MEF (fibroblast) [Raptor (mouse), knockdown] ( 50 ) , MEF (fibroblast) [RICTOR (mouse), knockdown] ( 50 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 96 ) , Mel-Ab (melanocyte) ( 110 ) , MES (pulmonary) ( 465 ) , mesangial ( 509 ) , microglia ( 362 ) , microvessel endothelial-lung [GIT1 (mouse), homozygous knockout] ( 43 ) , mIMCD-3 (epithelial) ( 535 , 560 ) , MIN6 (pancreatic) ( 148 , 300 ) , MLB13MYC (prechondroblast) ( 35 ) , MLE (epithelial) ( 442 ) , mLEC (epithelial) ( 103 ) , MLO-Y4 (osteoblast) ( 15 ) , MLP-29 ( 180 ) , MMTV-PyMT (breast cell) [JNK2 (mouse), homozygous knockout] ( 106 ) , mpkCCD (renal) ( 141 ) , MS1 (endothelial) ( 460 ) , myeloid ( 363 ) , myeloid-bone marrow ( 290 ) , myocyte-heart ( 31 , 211 , 326 , 372 , 418 , 441 ) , N18 (neuron) ( 520 ) , N1E-115 (neuron) ( 99 , 503 ) , Neuro-2a (neuron) ( 105 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 7 ) , NMuMG (epithelial) ( 550 ) , NSCLC (pulmonary) ( 111 ) , osteoclast ( 363 ) , P19 (testicular) ( 144 ) , PANC-1 (pancreatic) ( 131 ) , PC-12 (chromaffin) [TrkA (rat), transfection] ( 65 ) , PC-12 (chromaffin) ( 65 , 450 , 517 ) , preadipocyte ( 299 ) , preosteoclast ( 394 ) , prostate ( 67 ) , PYS-2 (epithelial) ( 145 ) , R1 ('stem, embryonic') ( 520 ) , R22 ('muscle, smooth') ( 298 ) , RAW 264 (macrophage) ( 446 ) , RAW 264.7 (macrophage) ( 29 , 113 , 189 , 190 , 191 , 192 , 198 ) , REF52 (fibroblast) ( 524 ) , SCC16-5 (fibroblast) ( 544 ) , skin ( 117 ) , skin [Fyn (mouse), transgenic] ( 151 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 213 ) , SN56 (neuron) ( 479 ) , Sor4 ( 452 , 461 ) , SorA ( 453 , 462 ) , spleen ( 183 ) , STC-1 (endocrine) ( 530 ) , stromal ( 98 ) , Swiss 3T3 (fibroblast) ( 193 , 498 ) , SYF (fibroblast) [Src (mouse), transfection] ( 61 ) , SYF (fibroblast) ( 125 , 298 , 386 ) , T lymphocyte ( 237 ) , T lymphocyte [FOXO1A (mouse), transgenic] ( 97 ) , T lymphocyte [PELI1 (mouse), homozygous knockout] ( 85 ) , T lymphocyte-blood ( 212 , 323 ) , T lymphocyte-lymph node ( 129 , 165 , 346 , 364 ) , T lymphocyte-lymph node [PRKD1 (mouse), genetic knockin] ( 121 ) , T lymphocyte-lymph node [PRKD2 (mouse), genetic knockin] ( 121 ) , T lymphocyte-spleen ( 115 , 375 ) , T lymphocyte-spleen [LAT (mouse), transgenic] ( 140 ) , T47D (breast cell) ( 373 ) , testis ( 176 , 178 , 182 ) , thymocyte ( 382 ) , thymocyte [CBL (mouse), homozygous knockout] ( 136 ) , thymus ( 177 , 181 ) , thyroid [BRAF (human), genetic knockin] ( 90 ) , uterus ( 22 ) , vascular smooth muscle cell ('muscle, smooth') ( 239 , 298 ) , VSMC-aorta ( 515 ) , WEHI-231 (B lymphocyte) ( 527 )

Upstream Regulation
Regulatory protein:
AIF1 (mouse) ( 24 ) , Akt1 (mouse) ( 552 ) , ALK (human) ( 135 ) , ARAF (human) ( 300 ) , ARAF (mouse) ( 300 ) , ARHGEF7 (mouse) ( 386 ) , ARRB1 (mouse) ( 148 ) , BAG1 (mouse) ( 421 ) , Bcl-10 (mouse) ( 364 ) , BCR-ABL1 (human) ( 376 ) , BRAF (human) ( 234 ) , BRAF (mouse) ( 493 ) , Brk (mouse) ( 125 ) , CAMK2D (human) ( 320 ) , CARD11 (mouse) ( 364 ) , CARD9 (mouse) ( 25 ) , CBL (mouse) ( 382 ) , Cbl-b (mouse) ( 382 ) , CD151 (mouse) ( 16 ) , CD44 (mouse) ( 383 ) , CD74 (mouse) ( 383 ) , CDC42 iso1 (mouse) ( 386 ) , CDK5R1 (mouse) ( 464 ) , Cot (mouse) ( 440 ) , dectin-1 (mouse) ( 25 ) , DLG3 (mouse) ( 355 ) , DOK3 (mouse) ( 53 ) , DRD1 (mouse) ( 469 ) , DUSP19 (mouse) ( 523 ) , DUSP3 (mouse) ( 523 ) , DUSP6 (mouse) ( 34 ) , EAR-2 (mouse) ( 237 ) , EGFR (mouse) ( 298 ) , eNOS (mouse) ( 326 ) , ERG (mouse) ( 67 ) , ERK2 (mouse) ( 54 , 396 ) , FADD (mouse) ( 30 ) , FAK iso2 (mouse) ( 473 , 549 ) , FAK iso9 (mouse) ( 385 ) , FCER1A (mouse) ( 305 ) , Fes (mouse) ( 210 , 536 ) , FGFR1 (human) ( 328 ) , FGFR2 (human) ( 463 ) , FLT3 (human) ( 426 ) , FLT3 (mouse) ( 175 ) , FMR1 (mouse) ( 5 , 390 ) , FOXP1 (mouse) ( 97 ) , GAB2 (mouse) ( 9 ) , GIPC1 (mouse) ( 132 ) , GIT1 (human) ( 43 ) , GLRX1 (mouse) ( 342 ) , GRB10 (human) ( 48 ) , GRB10 (mouse) ( 21 ) , HePTP (mouse) ( 212 ) , HRas (mouse) ( 68 , 111 , 551 ) , ICMT (mouse) ( 511 ) , IGF1R (mouse) ( 496 ) , IL17RD (mouse) ( 512 ) , IRS1 (mouse) ( 547 ) , ITGA9 (human) ( 369 ) , JAK2 (human) ( 290 , 526 ) , JNK2 (mouse) ( 20 , 68 , 106 ) , KRas (mouse) ( 44 , 67 , 378 , 556 ) , KSR (human) ( 118 ) , LAB (mouse) ( 375 ) , LAT (mouse) ( 140 ) , MAPKAPK2 (mouse) ( 317 ) , MAPKAPK3 (mouse) ( 317 ) , MEK1 (mouse) ( 103 , 524 ) , MEKK1 (mouse) ( 33 ) , mGluR5 (mouse) ( 304 ) , MIEN1 (human) ( 3 ) , MRas (human) ( 514 ) , MSK1 (human) ( 540 ) , MSK1 (mouse) ( 540 ) , MSK2 (mouse) ( 540 ) , MST1 (human) ( 131 ) , neurogranin (mouse) ( 534 ) , NPC1 (mouse) ( 437 , 548 ) , NPM1 (human) ( 135 ) , NYAP2 (mouse) ( 70 ) , PAG (rat) ( 270 ) , PAK1 (human) ( 524 ) , PDGFRA (mouse) ( 206 ) , PDK1 (mouse) ( 282 , 397 ) , PELI1 (mouse) ( 85 ) , PHLPP (human) ( 131 ) , PHLPP2 (human) ( 131 ) , PKCT (mouse) ( 297 ) , PPP1CC (human) ( 239 ) , PRKD1 (mouse) ( 498 ) , PTEN (mouse) ( 26 ) , PTP1B (mouse) ( 132 ) , PTPRB (mouse) ( 132 ) , PTPRJ (mouse) ( 132 ) , PTPRM (mouse) ( 132 ) , RAB11A (mouse) ( 132 ) , Rab7 (mouse) ( 132 ) , RAC1 (mouse) ( 524 ) , RAF1 (mouse) ( 524 ) , RAIG1 (mouse) ( 119 ) , Ret (human) ( 234 , 381 ) , RHOC (mouse) ( 66 ) , ROCK1 (mouse) ( 195 ) , SH3BP2 (mouse) ( 363 ) , SHC1 iso2 (human) ( 359 ) , SHP-2 (mouse) ( 179 , 533 ) , Src (human) ( 376 ) , Src (mouse) ( 61 , 66 ) , Syk (mouse) ( 289 ) , TAK1 (mouse) ( 372 ) , TBK1 (mouse) ( 378 ) , Tel (human) ( 526 ) , TSC2 (mouse) ( 127 , 387 ) , UCP2 (mouse) ( 357 ) , VEGFR3 (mouse) ( 103 ) , Vinculin (mouse) ( 494 ) , ZAP70 (mouse) ( 289 )
Putative in vivo kinases:
MEK1 (mouse) ( 560 , 567 )
Kinases, in vitro:
ERK2 (mouse) ( 564 , 566 ) , ERK2 (rat) ( 565 ) , Lck (mouse) ( 568 ) , MEK1 (human) ( 567 ) , MEK1 (mouse) ( 524 ) , MEK1 (rabbit) ( 564 , 565 ) , MEK1 (rat) ( 133 )
Putative upstream phosphatases:
PPP2CA (mouse) ( 536 )
Treatments:
15d-PGJ2 ( 484 ) , 17-beta-estradiol ( 22 ) , 1Na-PP1 ( 138 ) , 22-hydroxycholesterol ( 442 ) , 8-(3-chlorostyryl) caffeine ( 324 ) , 9d ( 209 ) , A23187 ( 553 ) , acadesine ( 500 ) , adriamycin ( 114 ) , AG1296 ( 426 ) , AG1478 ( 84 , 126 , 193 , 450 ) , AG490 ( 33 , 513 ) , AGEs ( 13 ) , Akt-I-1 ( 300 ) , Akt_activator_compound_11 ( 112 ) , Akt_inhibitor_VIII ( 208 ) , alloxazine ( 324 ) , alpha-lipoic_acid ( 105 ) , amino_acid_starvation ( 208 ) , amino_acids ( 208 ) , amphoterin ( 520 ) , angiopoietin-1 ( 460 ) , angiopoietin-2 ( 460 ) , anisomycin ( 317 , 540 , 553 ) , anti-CD3 ( 123 , 136 , 222 , 323 , 346 , 382 , 409 ) , anti-CD3/CD28 ( 97 , 115 , 136 , 375 ) , anti-CD4 ( 136 , 382 ) , anti-CD8 ( 382 ) , anti-Fas ( 233 ) , anti-IgB ( 289 ) , anti-IgE ( 179 ) , anti-IgM ( 137 , 166 ) , anti-ITGA4 ( 460 ) , anti-ITGA6 ( 460 ) , anti-ITGB3 ( 460 ) , antichymotrypsin ( 374 ) , antigenic stimulation ( 124 ) , antitrypsin ( 374 ) , aphidicolin ( 483 ) , apigenin ( 513 ) , apomorphine ( 432 ) , atorvastatin ( 324 ) , bacterial infection ( 122 ) , BAPTA-AM ( 528 , 530 , 541 ) , Bay61-3606 ( 124 ) , BDNF ( 55 , 138 , 561 ) , benzo(a)pyrene ( 348 ) , beta-amyloid_40 ( 479 ) , betaxolol ( 430 ) , BFD-22 ( 10 ) , BI-D1870 ( 13 , 165 , 317 ) , BIRA766 ( 124 ) , BIRB-0796 ( 317 ) , bisindolylmaleimide ( 520 ) , black_tea_polyphenols ( 117 ) , bombesin ( 193 , 498 ) , bradykinin ( 23 ) , brefeldin_A ( 175 ) , BRL37344 ( 466 ) , caffeine ( 361 ) , calphostin_C ( 520 ) , calyculin_A ( 556 ) , cAMP_analog ( 516 , 528 ) , cell_adhesion ( 212 ) , cell_detachment ( 494 ) , CGP77675 ( 501 ) , CGS_21680 ( 361 ) , chelerythrine ( 520 ) , ciclopirox_olamine ( 103 ) , cocaine ( 464 , 469 ) , cold_water_stress ( 356 ) , colforsin ( 118 , 361 , 445 , 459 , 503 , 528 , 534 ) , compound_56 ( 193 ) , compound_6 ( 139 ) , ConA ( 207 ) , curcumin ( 113 ) , curdlan ( 25 ) , CXCL12 ( 316 , 527 ) , cyclic_stretch ( 126 ) , cycloheximide ( 197 ) , cytochalasin_D ( 501 ) , DDA ( 212 ) , depolarization ( 478 ) , desmopressin ( 141 ) , DETA-NONOate ( 326 ) , dexamethasone ( 327 , 368 ) , DHPG ( 304 , 390 ) , differentiation ( 111 ) , DMNQ ( 239 ) , DNP ( 552 ) , DPCPX ( 324 ) , DPDPE ( 554 ) , dronabinol ( 39 ) , DTLET ( 554 ) , EDTA ( 460 ) , EGF ( 23 , 33 , 84 , 106 , 118 , 119 , 125 , 196 , 232 , 322 , 345 , 365 , 368 , 386 , 445 , 450 , 466 , 483 , 493 , 498 , 511 , 512 , 523 , 524 , 532 , 533 , 535 , 539 , 540 , 546 , 550 , 551 , 556 , 560 , 563 ) , EGTA ( 197 ) , Epo ( 149 , 290 , 417 , 542 ) , epoxomicin ( 180 ) , estradiol ( 479 , 543 ) , ethanol ( 529 , 538 ) , ether ( 356 ) , faslodex ( 373 , 479 ) , fedratinib ( 290 ) , FGF1 ( 2 , 139 , 225 , 522 ) , FGF2 ( 512 , 517 , 528 ) , fibronectin ( 445 , 524 , 562 ) , fingolimod ( 38 ) , fisetin ( 40 ) , FL ( 391 , 426 ) , fluid_shear_stress ( 15 ) , food deprivation ( 356 ) , G-CSF ( 369 ) , GDNF ( 234 ) , gefitinib ( 376 ) , gelatin ( 520 ) , GF109203X ( 193 , 528 ) , GH ( 403 ) , GLP-1 ( 148 ) , glucose ( 126 , 127 , 221 , 506 , 509 , 539 ) , GnRH ( 42 , 320 ) , Go_6976 ( 520 ) , guanosine ( 362 ) , GW4869 ( 32 ) , H-89 ( 118 , 148 , 212 , 373 , 445 , 503 , 520 ) , H2O2 ( 123 , 126 , 359 , 431 , 450 ) , haloperidol ( 430 ) , heparin sodium ( 394 ) , herstatin ( 532 ) , HGF ( 560 ) , honokiol ( 93 ) , hypertonic_buffer ( 419 ) , hypoxia ( 147 ) , IBMX ( 118 , 327 , 368 , 445 , 459 ) , ICI-118,551 ( 430 ) , IFN-alpha ( 184 ) , IFN-gamma ( 362 , 513 , 544 ) , IgE ( 552 ) , IGF-1 ( 31 , 410 , 465 , 466 , 496 , 506 , 539 , 556 , 557 ) , IGF-2 ( 410 ) , IL-18 ( 17 ) , IL-1b ( 440 ) , IL-3 ( 135 , 290 , 422 , 426 , 514 , 526 , 557 ) , IL-33 ( 29 ) , IL-4 ( 514 ) , IL-6 ( 358 ) , IL-9 ( 514 ) , imatinib ( 135 ) , insulin ( 12 , 46 , 54 , 93 , 127 , 195 , 208 , 221 , 263 , 282 , 297 , 299 , 327 , 329 , 392 , 393 , 410 , 443 , 466 , 497 , 508 , 541 , 547 , 551 ) , ionomycin ( 85 , 123 , 364 , 556 ) , ischemia/reperfusion ( 326 , 416 ) , isoproterenol ( 466 , 516 ) , iturelix ( 320 ) , JNK_inhibitor_I ( 358 ) , kainic_acid ( 502 ) , KGF ( 463 ) , KN-93 ( 320 ) , L-744,832 ( 556 ) , laminin-1 ( 520 ) , leptin ( 531 ) , levamfetamine ( 430 , 469 ) , licochalcone_A ( 198 ) , licochalcone_B ( 198 ) , licochalcone_C ( 198 ) , licochalcone_D ( 198 ) , LIF ( 395 , 474 ) , LIF withdrawal ( 14 ) , light ( 19 , 444 ) , lonafarnib ( 30 ) , long-term_potentiation ( 146 ) , low_glucose ( 126 ) , LPA ( 84 , 99 , 466 , 493 , 546 ) , LPS ( 20 , 53 , 104 , 113 , 198 , 317 , 357 , 446 , 484 , 538 ) , LY294002 ( 12 , 165 , 208 , 222 , 388 , 417 , 465 , 474 , 522 , 528 , 551 ) , M-CSF ( 330 , 363 , 525 , 536 ) , methotrexate ( 511 ) , methyl-beta-cyclodextrin ( 368 ) , methylphenidate ( 430 ) , MG132 ( 180 ) , midazolam ( 418 ) , MIF ( 383 ) , miR-181a ( 346 ) , MK801 ( 430 , 469 ) , MMS ( 387 ) , morphine ( 554 ) , MPTP ( 495 ) , MRS-1523 ( 324 ) , muramyl_dipeptide ( 98 ) , NAC ( 105 ) , nicotine ( 510 ) , nifedipine ( 148 ) , NMDA ( 355 ) , nocodazole ( 483 ) , nomifensine ( 495 ) , NP68 ( 165 ) , NSC697923 ( 33 ) , NTCU ( 348 ) , OH-BBN ( 303 ) , okadaic_acid ( 376 , 553 ) , orantinib ( 381 ) , OVA ( 121 ) , PACAP ( 444 ) , palmitate ( 297 , 325 ) , Pam3CSK4 ( 317 ) , papaverine ( 224 ) , PAR1-activating_peptide ( 518 ) , PD0325901 ( 30 ) , PD169316 ( 545 ) , PD184352 ( 22 , 317 , 540 ) , PD90059 ( 373 ) , PD98059 ( 12 , 13 , 42 , 105 , 122 , 300 , 358 , 422 , 442 , 465 , 466 , 479 , 484 , 503 , 513 , 515 , 517 , 519 , 521 , 522 , 528 , 531 , 545 , 551 , 556 , 557 , 560 ) , PDGF ( 65 , 206 , 339 , 342 , 512 , 515 , 546 , 549 ) , peptones ( 530 ) , PGE2 ( 15 , 116 , 314 ) , phorbol_ester ( 85 , 117 , 197 , 317 , 364 , 403 , 493 , 501 , 528 , 534 , 540 , 546 , 553 , 556 , 567 , 569 ) , pilocarpine ( 502 ) , PKC-theta_pseudosubstrate ( 297 ) , PKC412 ( 175 ) , poly-L-lysine ( 562 ) , pomegranate_wine ( 348 ) , PP1 ( 42 , 551 ) , PP2 ( 222 , 368 , 383 , 496 , 528 , 543 ) , prazosin ( 430 ) , progestin_R5020 ( 373 ) , propranolol ( 430 ) , PTH(1-34) ( 11 ) , PTX ( 503 ) , racepinefrine ( 516 ) , Raf1_kinase_inhibitor_I ( 300 ) , RANKL ( 363 ) , rapamycin ( 22 , 27 , 31 , 116 , 127 , 165 , 208 , 397 , 465 , 519 , 556 ) , refeeding ( 45 ) , restraint stress ( 58 ) , resveratrol ( 117 ) , retinoic_acid ( 442 , 520 ) , RGD ( 460 ) , RGE ( 460 ) , rimonabant ( 503 ) , rolipram ( 224 ) , rosiglitazone ( 93 ) , rottlerin ( 359 ) , S107 ( 58 ) , SB202190 ( 365 , 545 , 553 , 556 ) , SB203580 ( 197 , 317 , 501 , 540 ) , SCF ( 218 , 223 , 384 , 518 ) , SCH_23390 ( 430 , 469 ) , seliciclib ( 478 ) , semaxanib ( 381 ) , serum ( 197 , 233 , 397 , 431 , 493 , 512 , 546 , 554 , 556 ) , serum_withdrawal ( 521 ) , silibinin ( 303 ) , silymarin ( 303 ) , siRNA ( 329 , 386 ) , SKF82958 ( 502 ) , SL0101 ( 317 ) , SL327 ( 432 ) , SMI11293 ( 138 ) , sorbitol ( 563 ) , SP600125 ( 496 ) , sphingomyelin ( 32 ) , sphingosine_1-phosphate ( 26 , 110 ) , SPT ( 324 ) , staurosporine ( 359 ) , streptozotocin ( 389 ) , SU5402 ( 388 ) , SU6656 ( 376 ) , sunitinib ( 381 ) , TAK1_inhibitor ( 33 ) , TCAP-1 ( 57 ) , TCDD ( 368 ) , TDZD-8 ( 150 ) , TGF-alpha ( 532 , 539 ) , TGF-beta ( 33 , 90 , 298 , 537 , 550 ) , Theophylline ( 324 ) , thrombin ( 418 , 518 ) , thrombospondin ( 473 ) , TNF ( 317 , 331 , 362 , 440 , 555 ) , Torin1 ( 116 ) , triciribine ( 105 ) , TTX ( 475 ) , TUG-891 ( 8 ) , tunicamycin ( 175 ) , U0126 ( 49 , 57 , 90 , 103 , 113 , 123 , 127 , 148 , 184 , 197 , 208 , 212 , 234 , 289 , 300 , 322 , 324 , 328 , 368 , 384 , 388 , 403 , 426 , 431 , 459 , 474 , 478 , 479 , 503 , 518 , 520 , 521 , 522 , 528 , 535 , 553 ) , urethane ( 94 ) , UV ( 396 , 519 , 540 , 545 ) , vasopressin ( 193 , 498 ) , VEGF ( 132 , 139 ) , virus infection ( 1 ) , visual experience ( 475 ) , vitronectin ( 460 ) , WIN ( 39 , 503 ) , wortmannin ( 105 , 116 , 127 , 148 , 165 , 328 , 465 , 528 , 556 ) , Y27632 ( 501 ) , YM-254890 ( 8 ) , yohimbine ( 430 ) , Zn(2+) ( 138 ) , zymosan ( 553 )

Downstream Regulation
Effects of modification on ERK2:
enzymatic activity, induced ( 68 , 84 , 209 , 419 , 426 , 442 , 532 , 559 , 560 , 564 , 565 , 567 )
Effects of modification on biological processes:
apoptosis, inhibited ( 117 ) , carcinogenesis, induced ( 117 ) , carcinogenesis, inhibited ( 68 ) , cell growth, inhibited ( 68 ) , transcription, altered ( 553 ) , transcription, induced ( 23 )
Induce interaction with:
GAB1 (human) ( 560 )

Disease / Diagnostics Relevance
Relevant diseases:
cancer, squamous cell carcinoma ( 151 )

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71

Ren H (2011) CST Curation Set: 12902; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

72

Ren H (2011) CST Curation Set: 12903; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

73

Ren H (2011) CST Curation Set: 12904; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

74

Ren H (2011) CST Curation Set: 12905; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

75

Ren H (2011) CST Curation Set: 12906; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

76

Ren H (2011) CST Curation Set: 12893; Year: 2011; Biosample/Treatment: primary cells, B lymphocyte/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

77

Ren H (2011) CST Curation Set: 12894; Year: 2011; Biosample/Treatment: primary cells, B lymphocyte/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

78

Ren H (2011) CST Curation Set: 12895; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

79

Ren H (2011) CST Curation Set: 12896; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

80

Ren H (2011) CST Curation Set: 12897; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

81

Ren H (2011) CST Curation Set: 12898; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

82

Ren H (2011) CST Curation Set: 12900; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

83

Ren H (2011) CST Curation Set: 12901; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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Calbo J, et al. (2011) A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer. Cancer Cell 19, 244-56
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Georgiades SN, et al. (2011) Identification of a potent activator of Akt phosphorylation from a novel series of phenolic, picolinic, pyridino, and hydroxamic zinc(II) complexes. J Biol Inorg Chem 16, 195-208
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Ben P, et al. (2011) Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells. Int Immunopharmacol 11, 179-86
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Peidis P, et al. (2011) Doxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death. Cell Death Differ 18, 145-54
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Driessens G, et al. (2011) Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-γ1 phosphorylation. J Immunol 186, 784-90
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Kuehn HS, et al. (2011) Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. J Biol Chem 286, 391-402
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George J, et al. (2011) Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53. PLoS One 6, e23395
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Chen Y, et al. (2010) Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Res 70, 8917-26
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Wu Z, et al. (2010) MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice. J Clin Invest 120, 3901-11
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Chandrakesan P, et al. (2010) Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38. J Biol Chem 285, 33485-98
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Sanderson MP, et al. (2010) Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation. Mol Immunol 48, 171-8
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Bartolomé A, Guillén C, Benito M (2010) Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Endocrinology 151, 3084-94
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Iwai LK, Benoist C, Mathis D, White FM (2010) Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. J Proteome Res 9, 3135-45
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Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
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Qiao M, et al. (2010) Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Mol Cell 38, 512-23
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Chuck MI, Zhu M, Shen S, Zhang W (2010) The role of the LAT-PLC-gamma1 interaction in T regulatory cell function. J Immunol 184, 2476-86
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Zhou J (2010) CST Curation Set: 9105; Year: 2010; Biosample/Treatment: cell line, F9/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

143

Zhou J (2010) CST Curation Set: 9104; Year: 2010; Biosample/Treatment: cell line, ES J1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

144

Zhou J (2010) CST Curation Set: 9109; Year: 2010; Biosample/Treatment: cell line, P19/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

145

Zhou J (2010) CST Curation Set: 9108; Year: 2010; Biosample/Treatment: cell line, PY2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

146

Racaniello M, et al. (2010) Phosphorylation changes of CaMKII, ERK1/2, PKB/Akt kinases and CREB activation during early long-term potentiation at Schaffer collateral-CA1 mouse hippocampal synapses. Neurochem Res 35, 239-46
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Park YK, Park H (2010) Prevention of CCAAT/enhancer-binding protein beta DNA binding by hypoxia during adipogenesis. J Biol Chem 285, 3289-99
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Quoyer J, et al. (2010) GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem 285, 1989-2002
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Liron T, Nahari T, Souroujon MC, Neumann D (2010) Insertion of an NPVY sequence into the cytosolic domain of the erythropoietin receptor selectively affects erythropoietin-mediated signalling and function. Biochem J 427, 305-12
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Aguilar-Morante D, et al. (2010) Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8. PLoS One 5, e13879
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151

Zhao L, et al. (2009) Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53. Cancer Res 69, 9439-47
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152

Tucker M (2009) CST Curation Set: 8606; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

153

Tucker M (2009) CST Curation Set: 8603; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

154

Tucker M (2009) CST Curation Set: 8605; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

155

Tucker M (2009) CST Curation Set: 8607; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

156

Tucker M (2009) CST Curation Set: 8602; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

157

Tucker M (2009) CST Curation Set: 8561; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

158

Tucker M (2009) CST Curation Set: 8559; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

159

Tucker M (2009) CST Curation Set: 8562; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

160

Tucker M (2009) CST Curation Set: 8560; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST]
Curated Info

161

Tucker M (2009) CST Curation Set: 8555; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

162

Tucker M (2009) CST Curation Set: 8557; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

163

Tucker M (2009) CST Curation Set: 8558; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

164

Tucker M (2009) CST Curation Set: 8556; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

165

Salmond RJ, Emery J, Okkenhaug K, Zamoyska R (2009) MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells. J Immunol 183, 7388-97
19917692   Curated Info

166

Browne CD, et al. (2009) Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy. Immunity 31, 749-60
19896393   Curated Info

167

Tucker M (2009) CST Curation Set: 8089; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

168

Tucker M (2009) CST Curation Set: 8084; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

169

Tucker M (2009) CST Curation Set: 8081; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

170

Tucker M (2009) CST Curation Set: 8088; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

171

Tucker M (2009) CST Curation Set: 8077; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

172

Tucker M (2009) CST Curation Set: 8085; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

173

Tucker M (2009) CST Curation Set: 8080; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

174

Tucker M (2009) CST Curation Set: 8072; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

175

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140   Curated Info

176

Guo A (2009) CST Curation Set: 8168; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

177

Guo A (2009) CST Curation Set: 8170; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

178

Guo A (2009) CST Curation Set: 8167; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

179

McPherson VA, et al. (2009) SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc(epsilon)RI-induced activation of Fyn and Erk pathways leading to TNF(alpha) release from bone marrow-derived mast cells. J Immunol 183, 4940-7
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180

Santamaría E, et al. (2009) Regulation of stathmin phosphorylation in mouse liver progenitor-29 cells during proteasome inhibition. Proteomics 9, 4495-506
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181

Guo A (2009) CST Curation Set: 7710; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

182

Guo A (2009) CST Curation Set: 7709; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

183

Guo A (2009) CST Curation Set: 7708; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

184

Joshi S, et al. (2009) Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses. Proc Natl Acad Sci U S A 106, 12097-102
19574459   Curated Info

185

Zhou J (2009) CST Curation Set: 7383; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: QXp[ST]
Curated Info

186

Zhou J (2009) CST Curation Set: 7375; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: YXp[ST]
Curated Info

187

Zhou J (2009) CST Curation Set: 7376; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: YXp[ST]
Curated Info

188

Moritz A (2009) CST Curation Set: 7223; Year: 2009; Biosample/Treatment: cell line, BaF3/serum starved; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

189

Possemato A (2009) CST Curation Set: 7168; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

190

Possemato A (2009) CST Curation Set: 7169; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/MG132; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

191

Possemato A (2009) CST Curation Set: 7167; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

192

Possemato A (2009) CST Curation Set: 7166; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/control; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

193

Sinnett-Smith J, et al. (2009) Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation. J Biol Chem 284, 13434-45
19289471   Curated Info

194

Guo A (2009) CST Curation Set: 6839; Year: 2009; Biosample/Treatment: cell line, mouse lung fibroblasts/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb Cat#: 10001, PTMScan(R) Phospho-Akt Substrate Motif (RXRXXS*/T*) Immunoaffinity Beads Cat#: 1979
Curated Info

195

Lee DH, et al. (2009) Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem 284, 11776-80
19276091   Curated Info

196

Chung BM, et al. (2009) The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants. Oncogene 28, 1821-32
19305428   Curated Info

197

Tucker DE, et al. (2009) Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A2{alpha} in Regulating Interfacial Kinetics and Binding and Cellular Function. J Biol Chem 284, 9596-611
19176526   Curated Info

198

Furusawa J, et al. (2009) Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol 9, 499-507
19291859   Curated Info

199

Li Y (2009) CST Curation Set: 6302; Year: 2009; Biosample/Treatment: cell line, MEDF Ras V12 HDAC6-/+/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

200

Li Y (2009) CST Curation Set: 6303; Year: 2009; Biosample/Treatment: cell line, MEDF Ras V12 HDAC6-/+/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

201

Li Y (2009) CST Curation Set: 6297; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

202

Li Y (2009) CST Curation Set: 6298; Year: 2009; Biosample/Treatment: cell line, MEF Ras v12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

203

Li Y (2009) CST Curation Set: 6299; Year: 2009; Biosample/Treatment: cell line, MEF Ras v12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

204

Li Y (2009) CST Curation Set: 6296; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

205

Catalanotti F, et al. (2009) A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal. Nat Struct Mol Biol 16, 294-303
19219045   Curated Info

206

Olson LE, Soriano P (2009) Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell 16, 303-13
19217431   Curated Info

207

Das M, et al. (2009) Induction of hepatitis by JNK-mediated expression of TNF-alpha. Cell 136, 249-60
19167327   Curated Info

208

van Gorp AG, et al. (2009) AGC kinases regulate phosphorylation and activation of eukaryotic translation initiation factor 4B. Oncogene 28, 95-106
18836482   Curated Info

209

Tallent MK, et al. (2009) In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. J Biol Chem 284, 174-81
19004831   Curated Info

210

McPherson VA, et al. (2009) Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 29, 389-401
19001085   Curated Info

211

Lorenz K, Schmitt JP, Schmitteckert EM, Lohse MJ (2009) A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy. Nat Med 15, 75-83
19060905   Curated Info

212

Conche C, Boulla G, Trautmann A, Randriamampita C (2009) T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate. Immunity 30, 33-43
19144315   Curated Info

213

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

214

Stokes M (2008) CST Curation Set: 5664; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

215

Stokes M (2008) CST Curation Set: 5665; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

216

Stokes M (2008) CST Curation Set: 5666; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

217

Stokes M (2008) CST Curation Set: 5667; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

218

Simon C, et al. (2008) Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells. Blood 112, 4039-47
18753636   Curated Info

219

Kaneda T, et al. (2008) Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis. Cancer Lett 270, 354-61
18606490   Curated Info

220

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

221

Mariappan MM, et al. (2008) Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells. J Biol Chem 283, 30566-75
18701453   Curated Info

222

Bécart S, et al. (2008) Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity 29, 704-19
18976935   Curated Info

223

Samayawardhena LA, Pallen CJ (2008) Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells. J Biol Chem 283, 29175-85
18725415   Curated Info

224

Nishi A, et al. (2008) Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci 28, 10460-71
18923023   Curated Info

225

Partovian C, et al. (2008) Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. Mol Cell 32, 140-9
18851840   Curated Info

226

Rikova K (2008) CST Curation Set: 5292; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

227

Rikova K (2008) CST Curation Set: 5293; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

228

Rikova K (2008) CST Curation Set: 5294; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

229

Rikova K (2008) CST Curation Set: 5295; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

230

Rikova K (2008) CST Curation Set: 5296; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-4/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

231

Rikova K (2008) CST Curation Set: 5297; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-5/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

232

Mertins P, et al. (2008) Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics. Mol Cell Proteomics 7, 1763-77
18515860   Curated Info

233

Noble C, et al. (2008) CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol Cell 31, 862-72
18922468   Curated Info

234

Encinas M, et al. (2008) Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death Differ 15, 1510-21
18497757   Curated Info

235

Possemato A (2008) CST Curation Set: 5027; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

236

Possemato A (2008) CST Curation Set: 5028; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

237

Hermann-Kleiter N, et al. (2008) The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity. Immunity 29, 205-16
18701084   Curated Info

238

Rikova K (2008) CST Curation Set: 4985; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

239

Tchivilev I, et al. (2008) Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis. J Biol Chem 283, 22193-205
18540044   Curated Info

240

Possemato A (2008) CST Curation Set: 4930; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

241

Possemato A (2008) CST Curation Set: 4931; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

242

Possemato A (2008) CST Curation Set: 4932; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

243

Possemato A (2008) CST Curation Set: 4933; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

244

Possemato A (2008) CST Curation Set: 4934; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

245

Possemato A (2008) CST Curation Set: 4935; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

246

Possemato A (2008) CST Curation Set: 4936; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

247

Possemato A (2008) CST Curation Set: 4929; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

248

Luo W, et al. (2008) Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res 7, 3447-60
18563927   Curated Info

249

Stokes M (2008) CST Curation Set: 4845; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

250

Stokes M (2008) CST Curation Set: 4846; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

251

Stokes M (2008) CST Curation Set: 4847; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

252

Rikova K (2008) CST Curation Set: 4790; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KT-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

253

Rikova K (2008) CST Curation Set: 4775; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-4/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

254

Rikova K (2008) CST Curation Set: 4788; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-5/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

255

Rikova K (2008) CST Curation Set: 4769; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

256

Rikova K (2008) CST Curation Set: 4771; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

257

Rikova K (2008) CST Curation Set: 4839; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

258

Rikova K (2008) CST Curation Set: 4840; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

259

Rikova K (2008) CST Curation Set: 4837; Year: 2008; Biosample/Treatment: cell line, Dana Farber-L1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

260

Rikova K (2008) CST Curation Set: 4838; Year: 2008; Biosample/Treatment: cell line, Dana Farber-L2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

261

Rikova K (2008) CST Curation Set: 4763; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

262

Rikova K (2008) CST Curation Set: 4765; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

263

Cha HC, et al. (2008) Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. J Biol Chem 283, 18002-11
18408001   Curated Info

264

Li Y (2008) CST Curation Set: 4544; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

265

Li Y (2008) CST Curation Set: 4543; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

266

Li Y (2008) CST Curation Set: 4542; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

267

Li Y (2008) CST Curation Set: 4541; Year: 2008; Biosample/Treatment: cell line, 10T1/2/control; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

268

Rikova K (2008) CST Curation Set: 4476; Year: 2008; Biosample/Treatment: cell line, MD Ander 1158(393P)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

269

Rikova K (2008) CST Curation Set: 4481; Year: 2008; Biosample/Treatment: cell line, MD Ander a0859/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

270

Oneyama C, et al. (2008) The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src. Mol Cell 30, 426-36
18498747   Curated Info

271

Rikova K (2008) CST Curation Set: 4477; Year: 2008; Biosample/Treatment: cell line, MD Ander 1154/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

272

Rikova K (2008) CST Curation Set: 4478; Year: 2008; Biosample/Treatment: cell line, MD Ander 0895/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

273

Rikova K (2008) CST Curation Set: 4479; Year: 2008; Biosample/Treatment: cell line, MD Ander 1202(344SQ)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

274

Rikova K (2008) CST Curation Set: 4480; Year: 2008; Biosample/Treatment: cell line, MD Ander 1249/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

275

Rikova K (2008) CST Curation Set: 4474; Year: 2008; Biosample/Treatment: cell line, MD Ander 393LN/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

276

Rikova K (2008) CST Curation Set: 4475; Year: 2008; Biosample/Treatment: cell line, MD Ander 1169/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

277

Rikova K (2008) CST Curation Set: 4464; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

278

Rikova K (2008) CST Curation Set: 4437; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

279

Rikova K (2008) CST Curation Set: 4438; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

280

Rikova K (2008) CST Curation Set: 4439; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

281

Rikova K (2008) CST Curation Set: 4440; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

282

Bayascas JR, et al. (2008) Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol 28, 3258-72
18347057   Curated Info

283

Ren H (2008) CST Curation Set: 4335; Year: 2008; Biosample/Treatment: cell line, EGFR_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

284

Ren H (2008) CST Curation Set: 4336; Year: 2008; Biosample/Treatment: cell line, EGFR_M/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

285

Ren H (2008) CST Curation Set: 4337; Year: 2008; Biosample/Treatment: cell line, Ras_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

286

Zhou J (2008) CST Curation Set: 4322; Year: 2008; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

287

Zhou J (2008) CST Curation Set: 4323; Year: 2008; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

288

Zhou J (2008) CST Curation Set: 4325; Year: 2008; Biosample/Treatment: tissue, liver/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

289

Yasuda T, et al. (2008) Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity 28, 499-508
18356083   Curated Info

290

Wernig G, et al. (2008) Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer Cell 13, 311-20
18394554   Curated Info

291

Rikova K (2008) CST Curation Set: 4249; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

292

Rikova K (2008) CST Curation Set: 4250; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

293

Rikova K (2008) CST Curation Set: 4251; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

294

Rikova K (2008) CST Curation Set: 4252; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

295

Rikova K (2008) CST Curation Set: 4253; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

296

Rikova K (2008) CST Curation Set: 4254; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

297

Bakker W, et al. (2008) Protein kinase C theta activation induces insulin-mediated constriction of muscle resistance arteries. Diabetes 57, 706-13
18086904   Curated Info

298

Samarakoon R, Higgins SP, Higgins CE, Higgins PJ (2008) TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling. J Mol Cell Cardiol 44, 527-38
18255094   Curated Info

299

Krüger M, et al. (2008) Dissection of the insulin signaling pathway via quantitative phosphoproteomics. Proc Natl Acad Sci U S A 105, 2451-6
18268350   Curated Info

300

Alejandro EU, Johnson JD (2008) Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem 283, 2407-17
18006502   Curated Info

301

Takatori A, et al. (2008) Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2. Development 135, 23-32
18032450   Curated Info

302

Ballif BA, Carey GR, Sunyaev SR, Gygi SP (2008) Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. J Proteome Res 7, 311-8
18034455   Curated Info

303

Tyagi A, et al. (2007) Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Mol Cancer Ther 6, 3248-55
18089718   Curated Info

304

Hu HJ, et al. (2007) Metabotropic glutamate receptor 5 modulates nociceptive plasticity via extracellular signal-regulated kinase-Kv4.2 signaling in spinal cord dorsal horn neurons. J Neurosci 27, 13181-91
18045912   Curated Info

305

Cao L, et al. (2007) Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. J Immunol 179, 5864-76
17947660   Curated Info

306

Gu T (2007) CST Curation Set: 3402; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

307

Gu T (2007) CST Curation Set: 3403; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

308

Gu T (2007) CST Curation Set: 3404; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

309

Gu T (2007) CST Curation Set: 3405; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

310

Gu T (2007) CST Curation Set: 3406; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

311

Gu T (2007) CST Curation Set: 3407; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

312

Gu T (2007) CST Curation Set: 3408; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

313

Gu T (2007) CST Curation Set: 3409; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

314

Schenning M, van Tiel CM, Wirtz KW, Snoek GT (2007) The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein beta. Biochim Biophys Acta 1773, 1664-71
17683809   Curated Info

315

Robinson MJ, et al. (2007) Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. Mol Cell Biol 27, 7355-64
17709378   Curated Info

316

Le Y, et al. (2007) SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity 27, 811-23
18031698   Curated Info

317

Zaru R, et al. (2007) The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways. Nat Immunol 8, 1227-35
17906627   Curated Info

318

Yu J (2007) CST Curation Set: 3379; Year: 2007; Biosample/Treatment: cell line, Mouse Mesenchymal Stem Cells/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

319

Yu J (2007) CST Curation Set: 3380; Year: 2007; Biosample/Treatment: cell line, Mouse Mesenchymal Stem Cells/bFGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

320

Yamanaka A, et al. (2007) Involvement of CaM kinase II in gonadotropin-releasing hormone-induced activation of MAP kinase in cultured hypothalamic neurons. Arch Biochem Biophys 466, 234-41
17706588   Curated Info

321

Cho YY, et al. (2007) Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res 67, 8104-12
17804722   Curated Info

322

Falin RA, Cotton CU (2007) Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site. J Gen Physiol 130, 313-28
17724164   Curated Info

323

McNeill L, et al. (2007) The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses. Immunity 27, 425-37
17719247   Curated Info

324

Merla R, et al. (2007) The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylation. Am J Physiol Heart Circ Physiol 293, H1918-28
17616749   Curated Info

325

Jaeschke A, Davis RJ (2007) Metabolic stress signaling mediated by mixed-lineage kinases. Mol Cell 27, 498-508
17679097   Curated Info

326

Xuan YT, et al. (2007) Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pathway. Circulation 116, 535-44
17606840   Curated Info

327

Li X, et al. (2007) Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci U S A 104, 11597-602
17601773   Curated Info

328

Dong S, et al. (2007) 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood 110, 360-9
17389761   Curated Info

329

Yoshizaki T, et al. (2007) Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation. Mol Cell Biol 27, 5172-83
17515613   Curated Info

330

Takeshita S, et al. (2007) c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. J Biol Chem 282, 18980-90
17420255   Curated Info

331

Schlaepfer DD, et al. (2007) Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. J Biol Chem 282, 17450-9
17438336   Curated Info

332

Guo A (2007) CST Curation Set: 2987; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

333

Guo A (2007) CST Curation Set: 2988; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

334

Guo A (2007) CST Curation Set: 2989; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

335

Guo A (2007) CST Curation Set: 2990; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

336

Guo A (2007) CST Curation Set: 2983; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

337

Guo A (2007) CST Curation Set: 2985; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

338

Guo A (2007) CST Curation Set: 2986; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

339

Artemenko Y, Gagnon A, Ibrahim S, Sorisky A (2007) Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes. J Cell Physiol 211, 598-607
17219406   Curated Info

340

Guo A (2007) CST Curation Set: 2921; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E) Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CKII Substrate Antibody (polyAb) Cat#: 5808, PTMScan(R) Phospho-CK Substrate Motif (S*/T*D/EXD/E) Immunoaffinity Beads Cat#: 1994
Curated Info

341

Guo A (2007) CST Curation Set: 2923; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E) Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CKII Substrate Antibody (polyAb) Cat#: 5808, PTMScan(R) Phospho-CK Substrate Motif (S*/T*D/EXD/E) Immunoaffinity Beads Cat#: 1994
Curated Info

342

Xing K, et al. (2007) Low molecular weight protein tyrosine phosphatase (LMW-PTP) and its possible physiological functions of redox signaling in the eye lens. Biochim Biophys Acta 1774, 545-55
17428749   Curated Info

343

Guo A (2007) CST Curation Set: 2827; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

344

Guo A (2007) CST Curation Set: 2830; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

345

Jo M, et al. (2007) Urokinase receptor primes cells to proliferate in response to epidermal growth factor. Oncogene 26, 2585-94
17043637   Curated Info

346

Li QJ, et al. (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129, 147-61
17382377   Curated Info

347

Guo A (2007) CST Curation Set: 2718; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E)
Curated Info

348

Khan N, et al. (2007) Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res 67, 3475-82
17389758   Curated Info

349

Guo A (2007) CST Curation Set: 2672; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

350

Guo A (2007) CST Curation Set: 2675; Year: 2007; Biosample/Treatment: tissue, brain/LY; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

351

Guo A (2007) CST Curation Set: 2677; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

352

Guo A (2007) CST Curation Set: 2682; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

353

Guo A (2007) CST Curation Set: 2564; Year: 2007; Biosample/Treatment: cell line, C2C12-D/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

354

Guo A (2007) CST Curation Set: 2565; Year: 2007; Biosample/Treatment: cell line, C2C12-D/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

355

Cuthbert PC, et al. (2007) Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci 27, 2673-82
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356

Ikeda Y, Ishiguro K, Fujita SC (2007) Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS Lett 581, 891-7
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357

Emre Y, et al. (2007) Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochem J 402, 271-8
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358

Andreozzi F, et al. (2007) Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells. Mol Cell Biol 27, 2372-83
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359

Hu Y, Kang C, Philp RJ, Li B (2007) PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. Cell Signal 19, 410-8
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360

Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93
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361

Sahin B, et al. (2007) Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling. Brain Res 1129, 1-14
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362

D'Alimonte I, et al. (2007) Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells. J Immunol 178, 720-31
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363

Ueki Y, et al. (2007) Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell 128, 71-83