Ser733
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser733  -  IKKB (human)

Site Information
TVREQDQsFtALDWs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 5014908

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PLK1 (human) ( 2 )

Downstream Regulation
Effects of modification on IKKB:
molecular association, regulation ( 2 )
Inhibit interaction with:
IKKG (human) ( 2 )

References 

1

Meyer AN, et al. (2013) Tyrosine phosphorylation allows integration of multiple signaling inputs by IKK╬▓. PLoS One 8, e84497
24386391   Curated Info

2

Higashimoto T, Chan N, Lee YK, Zandi E (2008) Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. J Biol Chem 283, 35354-67
18957422   Curated Info