Lys19
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Home > Acetylation Site Page: > Lys19  -  CTNNB1 (human)

Site Information
MAMEPDRkAAVsHWQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 5013900

In vivo Characterization
Methods used to characterize site in vivo:
[14C] acetate labeling ( 3 ) , immunoprecipitation ( 1 , 3 ) , mutation of modification site ( 1 , 3 ) , western blotting ( 1 , 3 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on CTNNB1:
intracellular localization ( 3 ) , protein stabilization ( 3 )
Effects of modification on biological processes:
carcinogenesis, inhibited ( 3 ) , cell motility, induced ( 3 ) , transcription, induced ( 3 )

References 

1

Chen DQ, et al. (2023) Poricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylation. Acta Pharmacol Sin 44, 1038-1050
36470978   Curated Info

2

Shares BH, et al. (2018) Active mitochondria support osteogenic differentiation by stimulating ¿¿-catenin acetylation. J Biol Chem
30150300   Curated Info

3

Ge X, et al. (2009) PCAF acetylates {beta}-catenin and improves its stability. Mol Biol Cell 20, 419-27
18987336   Curated Info