Arg337

Site Information
LQIrGrErFEMFREL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 5009201

In vivo Characterization
Methods used to characterize site in vivo:	flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	bone cancer ( 1 )
Relevant cell line - cell type - tissue:	Saos-2 (bone cell) ( 1 ) , U2OS (bone cell) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	apoptosis, inhibited ( 1 ) , cell cycle regulation ( 1 ) , transcription, altered ( 1 )
Induce interaction with:	53BP1 (human) ( 1 )

References
1	Jansson M, et al. (2008) Arginine methylation regulates the p53 response. Nat Cell Biol 10, 1431-9 19011621 Curated Info