Ser641
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Home > Phosphorylation Site Page: > Ser641  -  GYS1 (rat)

Site Information
YRYPRPAsVPPsPSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448237

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 4 ) , phospho-antibody ( 3 , 5 ) , western blotting ( 3 , 5 )
Relevant cell line - cell type - tissue:
'muscle, skeletal' ( 3 , 5 ) , heart ( 4 ) , muscle ( 4 )

Upstream Regulation
Treatments:
fasting ( 5 ) , insulin ( 3 , 5 ) , muscle contraction ( 3 , 5 ) , refeeding ( 5 )

References 

1

Pérez-Mendoza M, Rivera-Zavala JB, Díaz-Muñoz M (2014) Daytime restricted feeding modifies the daily variations of liver gluconeogenesis: adaptations in biochemical and endocrine regulators. Chronobiol Int 31, 815-28
24766192   Curated Info

2

Monteserin-Garcia J, et al. (2013) Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis. FASEB J 27, 1561-71
23292070   Curated Info

3

Lin FC, et al. (2012) Effect of insulin and contraction on glycogen synthase phosphorylation and kinetic properties in epitrochlearis muscles from lean and obese Zucker rats. Am J Physiol Cell Physiol 302, C1539-47
22403789   Curated Info

4

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

5

Lai YC, Zarrinpashneh E, Jensen J (2010) Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents. J Appl Physiol 108, 1106-15
20185632   Curated Info