Ser20

Site Information
PLsQEtFsCLWKLLP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 447529

In vivo Characterization
Methods used to characterize site in vivo:	phospho-antibody ( 2 , 3 ) , western blotting ( 2 , 3 )
Disease tissue studied:	brain cancer ( 2 ) , glioma ( 2 )
Relevant cell line - cell type - tissue:	C6 (glial) ( 2 ) , myocyte-heart ( 3 )

Upstream Regulation
Treatments:	acetominophen ( 2 ) , angiotensin_2 ( 3 ) , etoposide ( 2 ) , fluorouracil ( 2 )

References
1	Gogna R, et al. (2013) p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. EMBO Mol Med 5, 1662-83 24096875 Curated Info
2	Lee YS, et al. (2006) Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen. J Pharmacol Exp Ther 317, 202-8 16330492 Curated Info
3	Grishko V, et al. (2003) Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: role of DNA damage. Am J Physiol Heart Circ Physiol 285, H2364-72 12919932 Curated Info