Ser937

Site Information
QMVLSRGsIFPVSVP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 468039

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 6 ) , mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 7 ) , mutation of modification site ( 6 ) , phospho-antibody ( 6 ) , western blotting ( 6 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 2 ) , brain ( 3 , 5 ) , COS (fibroblast) ( 6 ) , kidney ( 4 ) , liver ( 1 , 7 ) , parotid acinar ( 6 )

Downstream Regulation
Effects of modification on IP3R2:	activity, induced ( 6 )

References
1	Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86 23567750 Curated Info
2	Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20 23684622 Curated Info
3	Trinidad JC, et al. (2012) Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics 11, 215-29 22645316 Curated Info
4	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
5	Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9 20415495 Curated Info
6	Betzenhauser MJ, Fike JL, Wagner LE, Yule DI (2009) Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937. J Biol Chem 284, 25116-25 19608738 Curated Info
7	Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93 17242355 Curated Info