Phosphorylation Site Page:
In vivo Characterization
Methods used to characterize site
mass spectrometry ( 1, 2, 3)
Disease tissue studied:
breast cancer ( 1), breast ductal carcinoma ( 1), breast cancer, triple negative ( 1), lung cancer ( 2), non-small cell lung adenocarcinoma ( 2), ovarian cancer ( 1)
Relevant cell line - cell type - tissue:
breast ( 1), Jurkat (T lymphocyte) ( 3), lung ( 2), ovary ( 1)
Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
Mol Cell Proteomics 13, 1690-704
Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors.
J Proteomics 91, 286-96
Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment.
Nat Methods 10, 634-7