Tyr110
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Home > Phosphorylation Site Page: > Tyr110  -  TRPV4 (mouse)

Site Information
PMDSLFDyGTYRHHP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4777176

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , microscopy-colocalization with upstream kinase ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , MDCK (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )
Treatments:
H2O2 ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on TRPV4:
activity, induced ( 1 ) , intracellular localization ( 1 )

References 

1

Wegierski T, et al. (2009) Tyrosine Phosphorylation Modulates the Activity of TRPV4 in Response to Defined Stimuli. J Biol Chem 284, 2923-33
19033444   Curated Info

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