Ser119
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Home > Phosphorylation Site Page: > Ser119  -  ITPKA (mouse)

Site Information
LQQPRRLstSSLSST   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4763186

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'neuron, hippocampal'-brain ( 1 ) , 293 (epithelial) ( 1 ) , brain ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Treatments:
H-89 ( 1 ) , NKH_477 ( 1 )

Downstream Regulation
Effects of modification on ITPKA:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 ) , neural plasticity ( 1 )

References 

1

Lee D, et al. (2012) Inositol 1,4,5-trisphosphate 3-kinase A is a novel microtubule-associated protein: PKA-dependent phosphoregulation of microtubule binding affinity. J Biol Chem 287, 15981-95
22389500   Curated Info